It’s Time to Reevaluate Rinse™
Brushing and interdental cleaning are foundational to oral health, but they do not adequately address plaque biofilm throughout the oral cavity3. Formulated with a proprietary blend of 4 Essential Oils (eucalyptol, menthol, methyl salicylate, and thymol), LISTERINE® antiseptic mouthwashes work synergistically with brushing and interdental cleaning to reduce bacterial load and penetrate plaque biofilm deeper than mechanical methods alone1&5.
Watch the video below to learn more1-9.
References
1. Bosma, M. L., McGuire, J. A., DelSasso, A., Milleman, J., & Milleman, K. (2024). Efficacy of flossing and mouth rinsing regimens on plaque and gingivitis: a randomized clinical trial. BMC oral health, 24(1), 178. https://doi.org/10.1186/s12903-024-03924-4
2. Hoch, C. C., Petry, J., Griesbaum, L., Weiser, T., Werner, K., Ploch, M., Verschoor, A., Multhoff, G., Bashiri Dezfouli, A., & Wollenberg, B. (2023). 1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 167, 115467. https://doi.org/10.1016/j.biopha.2023.115467
3. Kerr, W. J., Kelly, J., & Geddes, D. A. (1991). The areas of various surfaces in the human mouth from nine years to adulthood. Journal of dental research, 70(12), 1528–1530. https://doi.org/10.1177/00220345910700121001
4. Marchese, A., Orhan, I. E., Daglia, M., Barbieri, R., Di Lorenzo, A., Nabavi, S. F., Gortzi, O., Izadi, M., & Nabavi, S. M. (2016). Antibacterial and antifungal activities of thymol: A brief review of the literature. Food chemistry, 210, 402–414. https://doi.org/10.1016/j.foodchem.2016.04.111
5. Milleman, J., Bosma, M. L., McGuire, J. A., Sunkara, A., McAdoo, K., DelSasso, A., Wills, K., & Milleman, K. (2022). Comparative Effectiveness of Toothbrushing, Flossing and Mouthrinse Regimens on Plaque and Gingivitis: A 12-week virtually supervised clinical trial. Journal of dental hygiene : JDH, 96(3), 21–34.
6. Patel, T., Ishiuji, Y., & Yosipovitch, G. (2007). Menthol: a refreshing look at this ancient compound. Journal of the American Academy of Dermatology, 57(5), 873–878. https://doi.org/10.1016/j.jaad.2007.04.008
7. Song, X., Li, R., Zhang, Q., He, S., & Wang, Y. (2022). Antibacterial Effect and Possible Mechanism of Salicylic Acid Microcapsules against Escherichia coli and Staphylococcus aureus. International Journal of Environmental Research and Public Health, 19(19), 12761. https://doi.org/10.3390/ijerph191912761
8. Trombetta, D., Castelli, F., Sarpietro, M. G., Venuti, V., Cristani, M., Daniele, C., Saija, A., Mazzanti, G., & Bisignano, G. (2005). Mechanisms of antibacterial action of three monoterpenes. Antimicrobial agents and chemotherapy, 49(6), 2474–2478. https://doi.org/10.1128/AAC.49.6.2474-2478.2005
9.Versteeg N, Wellauer V, Wittenwiler S, Aerenhouts D, Clarys P and Clijsen R (2024) Short-term cutaneous vasodilatory and thermosensory effects of topical methyl salicylate. Front. Physiol. 15:1347196. doi: 10.3389/fphys.2024.1347196
