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How ROGAINE® works to regrow hair​

Learn about topical minoxidil’s mechanism of action and see the five unique ways ROGAINE® works to help reactivate the natural hair regrowth cycle

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Topical minoxidil mechanism of action

Topical minoxidil has been shown to stimulate follicular DNA synthesis, directly affect the proliferation and differentiation of follicular keratinocytes in vitro, and shown to regulate hair physiology independently of blood flow influences. 1,2,3,4

1. Sánchez-Díaz M, López-Delgado D, Montero-Vílchez T, Salvador-Rodríguez L, Molina-Leyva A, Tercedor-Sánchez J, Arias-Santiago S. Systemic Minoxidil Accidental Exposure in a Paediatric Population: A Case Series Study of
2. Cutaneous and Systemic Side Effects. J Clin Med. 2021 Sep 20;10(18):4257. 3. DrugPoints® System. Merative. 2023. In: STAT!Ref Online Electronic Medical Library. https://online.statref.com/document/q4RA4-lnluUZT1pyvvWrvt. Accessed November 15, 2023​
4. Patel P, Nessel TA, Kumar D D. Minoxidil. [Updated 2023 Nov 15]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482378/​