Randomized clinical efficacy trial of potassium oxalate mouthrinse in relieving dentinal sensitivity

The theorized mechanism of dentine sensitivity is based on the hydrodynamic theory proposed by Brännström, suggesting that dentine tubules exposed to thermal, evaporative, tactile or osmotic stimuli lead to brief, sharp, well-localized pain in patients.

Occlusion of exposed dentine tubules has been shown to relieve from dentine sensitivity and pain. This study demonstrates the efficacy in relieving dentine sensitivity of 4 weeks’ treatment with an alcohol-free mouthrinse comprising 1.4% potassium oxalate (KO) (Listerine^® Advanced Defence Sensitive; LADS), compared with negative and positive controls.