LISTERINE Clinical Solutions™

From the leaders in science-based mouthwashes

Introducing our line of advanced, targeted solutions that take our science to a whole new level.

Supported by clinical studies involving dentists and dental hygienists

LISTERINE® does not decrease salivary flow^1†

LISTERINE® does not decrease oral pH^1†

Backed by science

Supported by clinical studies^1-³

Formulated with essential oils

Read more

Gum Therapy

for 3X healthier gums in just one week^‡

Enamel Repair

works on contact^§ to repair weakened enamel

Formulated with 67% more zinc chloride than any other LISTERINE product⁴

Works in two ways to restore gingival health:

Contains essential oils to kill 99.9% of germs that cause dental plaque and gingivitis⁵^,⁶
Formulated with more zinc chloride to reduce subgingival bacteria²^,³

Clinically proven to reduce bleeding gums by 1 week vs brushing alone with its new formula with more zinc chloride²

Clinically proven to treat gingivitis for 3X healthier gums in 1 week^2‡

Works on contact to repair weakened enamel^4§

7x greater fluoride uptake and 68% greater re-mineralization than ACT® Total Care Anti-cavity Fluoride Mouthwash^‖
Fluoride combines with calcium and phosphate ions to create mineral fluorapatite that fills in weakened enamel and helps strengthen the enamel matrix
- Provides 24-hour cavity protection (when used twice daily)

This technology rapidly binds calcium and phosphate ions with fluoride to create reservoirs that enhance fluoride delivery to teeth.⁴

LISTERINE Clinical Solutions™ have a non-drying formula that demonstrated no effect on salivary flow rate^1†

LISTERINE Clinical Solutions™ are formulated to conserve oral pH levels^1†

#1 Dentist recommended mouthwash brand. *IQVIA ProVoice Survey, May 2024.

†Vs brushing alone in health adults with normal salivary flow.

‡When used twice daily, vs brushing and flossing alone.

§Vigorously swish 10 mL (2 teaspoonfuls) of rinse between your teeth for 1 minute and then spit out.

‖Based on the results of an in vitro enamel fluoride reuptake study. Data on File, Kenvue Canada Inc. 2025.

References

^{Bosma ML, DelSasso A, McGuire A,}^{et al.}^{Two-week safety, salivary pH and flow – alcohol/non-alcohol mouthrinses. Presented at: 2023 IADR/LAR General Session & Exhibition with WCPD; June 21–24, 2023; Bogotá, Columbia.}
^{Milleman KR, Bosma ML, DelSasso,}^{et al.}^{Safety and efficacy of essential oil and zinc containing mouthrinses. Presented at: Presented at: 2023 IADR/LAR General Session & Exhibition with WCPD; June 21–24, 2023; Bogotá, Columbia.}
^{Min K, Bosma ML, John G,}^{et al}^{. Quantitative analysis of the effects of brushing, flossing, and mouthrinsing on supragingival and subgingival plaque microbiota: 12-week clinical trial.}^{BMC Oral Health.}^2024;24:575.
^{Data on File. Kenvue Canada Inc.}
^{Pan P, Barnett ML, Coelho J,}^{et al}^{. Determination of the in situ bactericidal activity of an essential oil mouthrinse using a vital stain method. J Clin}^Periodontol.^{2000;27(4):256-261.}
^{Ilg D, Junker L, McGuire JA,}^{et al}^{. In vivo efficacy of an alcohol-free essential oil containing mouthrinse.}^{J Dent Hyg.}^{2012;86(1):51.}