Introducing our line of advanced, targeted solutions that take our science to a whole new level.
Supported by clinical studies involving dentists and dental hygienists1–3
LISTERINE® does not decrease salivary flow1†
LISTERINE® does not decrease oral pH1†
Gum Therapy
for 3X healthier gums in just one week‡
Sensitivity Relief
for effective and continual relief from the pain of sensitive teeth§
Enamel Repair
works on contactǁ to repair weakened enamel
Breath Defence
with odour-neutralizing technology to prevent bad breath for 24 hours¶
LISTERINE Clinical Solutions® Gum Therapy
Formulated with 67% more zinc chloride than any other LISTERINE® product4
Works in two ways to restore gingival health:
Contains essential oils to reduce 99.9% of germs that cause dental plaque and gingivitis5,6
Reduces subgingival bacteria and shifts the microbiome to a healthier state2,3
Reduced bleeding gums
Clinically proven to reduce bleeding gums by 1 week vs brushing alone with its new formula with more zinc chloride2
Reduced gingivitis to restore gingival health
Clinically proven to treat gingivitis for 3X healthier gums in 1 week2‡
LISTERINE Clinical Solutions® Sensitivity Relief
Formulated with CRYSTAL BLOCK Technology™
·Formulated with potassium oxalate to create a protective barrier against the sharp sensation of pain caused by tooth sensitivity
Open tubules are blocked by stable crystals deposited both on the surface of the dentin and deep inside the tubules4,7
Provides tough and durable occlusion vs competitive occlusive toothpaste4,7
Tubule occlusions remain resistant and minimally affected by acid or mechanical interference
Occlusion from competitive toothpastes erodes by as much as 50% after mechanical and acid challenges**
Blocks 97% of dentin tubules in just 6 rinses7
Achieves 99% occlusion after 12 rinses7
Maintains 91% tubule blockage even after an acidic challenge7
LISTERINE Clinical Solutions® Enamel Repair
Works on contact to repair weakened enamel4§
7X greater fluoride uptake and 68% greater re-mineralization than ACT® Total Care Anti-cavity Fluoride Mouthwash††
Provides 24-hour cavity protection when used twice daily
Powered by Rapid Fusion Technology™
This technology rapidly binds calcium ions with fluoride to create reservoirs that enhance fluoride delivery to teeth4
LISTERINE Clinical Solutions® Breath Defence
A triple-action alcohol-free mouthwash formula that immediately kills odour-causing bacteria
Neutralizes and kills 2 sources of malodor and stubborn bad breath for 24 hours‖
Uses zinc and odour-neutralizing technology to counteract odour molecules such as coffee, garlic, and onion
Safety information
LISTERINE Clinical Solutions® have a non-drying formula that demonstrated no effect on salivary flow rate
LISTERINE Clinical Solutions® are formulated to conserve oral pH levels1†
*IQVIA ProVoice Survey, May 2024.
†Vs brushing alone in healthy adults with normal salivary flow.
‡When used twice daily, vs brushing and flossing alone.
§With regular use.
ǁVigorously swish 10 mL (2 teaspoonfuls) of rinse between your teeth for 1 minute and then spit out.
¶When used twice daily.
**In laboratory studies.
††Based on the results of an in vitro enamel fluoride reuptake study. Data on File, Kenvue Canada Inc. 2025.
References
Bosma ML, DelSasso A, McGuire A, et al. Two-week safety, salivary pH and flow – alcohol/non-alcohol mouthrinses. Presented at: 2023 IADR/LAR General Session & Exhibition with WCPD; June 21–24, 2023; Bogotá, Columbia.
Milleman KR, Bosma ML, DelSasso A, et al. Safety and efficacy of essential oil and zinc containing mouthrinses. Presented at: Presented at: 2023 IADR/LAR General Session & Exhibition with WCPD; June 21–24, 2023; Bogotá, Columbia.
Min K, Bosma ML, John G, et al. Quantitative analysis of the effects of brushing, flossing, and mouthrinsing on supragingival and subgingival plaque microbiota: 12-week clinical trial. BMC Oral Health. 2024;24:575.
Data on File. Kenvue Canada Inc.
Pan P, Barnett ML, Coelho J, et al. Determination of the in situ bactericidal activity of an essential oil mouthrinse using a vital stain method. J Clin Periodontol. 2000;27(4):256-261.
Ilg D, Junker L, McGuire JA, et al. In vivo efficacy of an alcohol-free essential oil containing mouthrinse. J Dent Hyg. 2012;86(1):51.
Sharma D, Hong CX, Heipp PS. A novel potassium oxalate-containing tooth-desensitising mouthrinse: A comparative in vitro study. J Dent. 2013;41(Suppl 4):S18-S27.