English ivy leaf (Hedera helix)
Native to many parts of Europe, English ivy leaf has a long history of helping to clear mucus, and studies also suggest that it safely helps with cough associated with hoarseness, dry throat, and irritants.1*
Properties and mechanism of action
Ivy leaf contains saponins, flavonoids, and other phenolic compounds, and exhibits respiratory-supporting properties.1* While the exact mechanism of action is not known, the saponins in ivy leaf are believed to help clear mucus from the chest and to induce relaxation of the airway.2* It has also been observed that ivy leaf both widens the bronchi in the lungs and stimulates bronchial glands to secrete fluid.3*
Scientific support
The benefits of ivy leaf extract in improving cough associated with hoarseness, dry throat, and irritants* have been demonstrated in multiple clinical trials involving both adults and children.1,4
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Ingredient details are provided as general information and are not intended to be associated with any specific Zarbee’s® products.
REFERENCES:
1. Lang C, Röttger-Lüer P, Staiger C. A valuable option for the treatment of respiratory diseases: review on the clinical evidence of the ivy leaves dry extract EA 575®. Planta Med. 2015;81(12-13):968-974. 2. Wolf A, Gosens R, Meurs H, Häberlein H. Pre-treatment with α-hederin increases β-adrenoceptor mediated relaxation of airway smooth muscle. Phytomedicine. 2011;18(2-3):214-218. 3. Ivy leaf. European medicines agency science medicines health. Published November 21, 2017. Accessed July 7, 2021. https://www.ema.europa.eu/en/documents/herbal-summary/ivy-leaf-summary-public_en-0.pdf
4. Fazio S, Pouso J, Dolinsky D, et al. Tolerance, safety and efficacy of Hedera helix extract in inflammatory bronchial diseases under clinical practice conditions: a prospective, open, multicentre postmarketing study in 9657 patients. Phytomedicine. 2009;16(1):17-24.