The PEPCID® Difference
On-demand heartburn relief that starts in minutes* —and lasts all day or all night†
Recommend the original famotidine brand
The famotidine brand with decades of clinically proven heartburn relief‡
#1 doctor and gastroenterologist recommended acid reducer brand among OTC histamine-2 (H2) blockers
Fast relief in 3 formulations:
» Original and Maximum Strength PEPCID AC® prevent and relieve heartburn in minutes*
» PEPCID COMPLETE® is a dual-action antacid & acid reducer that starts working in secondsPEPCID® products control acid all day or all night†
One tablet prevents§ heartburn before it starts and controls acid all night†
See how PEPCID® works different than proton pump inhibitors (PPIs)
PEPCID® (famotidine) does not contain ranitidine, which FDA had requested manufacturers withdraw from market in 20191
Rely on the clinically proven safety and efficacy profile of PEPCID®‡
Evaluated in 50+ clinical studies and backed by pioneering research. The first famotidine brand made available directly to consumers.
Patients can start and stop PEPCID® as they need it, and rely on it to work in minutes* before, during, or after eating.
The PPI omeprazole (Prilosec®) requires additional screening for patients taking concomitant warfarin or high-dose methotrexate.2,3 Prilosec® has been shown to increase the risk of Clostridium difficile-associated diarrhea.3,4 Remember to ask your patients about what other prescriptions they are taking.
When antacids aren’t enough and ppis may not be needed, rely on PEPCID® for occasional heartburn
Compare heartburn treatments:
Antacids
Neutralize existing gastric acid in stomach
Can last up to 2 hours
Cannot prevent heartburn symptoms
PEPCID®
Starts to relieve heartburn in 15 to 30 minutes||; PEPCID COMPLETE® starts to work in seconds
Lasts all day or all night,† even when taken occasionally as needed
PEPCID AC® and Maximum Strength PEPCID AC® can prevent heartburn before it starts§
PPIs
May take 1 to 4 days to begin relieving symptoms for frequent heartburn3¶
Must be taken daily for 2 weeks at prescribed time for optimal efficacy5
Course of treatment is 2 weeks no more than once every 4 months; is not indicated for immediate heartburn relief3
Compare otc famotidine brands, and discover the PEPCID® difference
The only famotidine brand that’s this complete
PEPCID COMPLETE® combines:
An antacid that immediately starts neutralizing acid plus
The H2 blocker famotidine that helps control acid all day or all night†
No other brand is both faster and longer-lasting at neutralizing and controlling acid than PEPCID COMPLETE®.
*Begins to work in 15 to 30 minutes.
†Based on 9-hour acid control studies during the day and 12-hour acid control studies during the night. Acid control does not imply symptom relief.
‡When used as directed.
§PEPCID AC® and Maximum Strength PEPCID AC® can prevent heartburn when taken 15 to 60 minutes before a meal.
||PEPCID AC® and Maximum Strength PEPCID AC®.
¶Some users may feel relief as soon as 24 hours after first dose.
References:
1. FDA requests removal of all ranitidine products (Zantac) from the market. News release. US Food and Drug Administration. April 1, 2020. Accessed April 9, 2020. https://www.fda.gov/news-events/press-announcements/fda-requests-removal-all-ranitidine-products-zantac-market 2. De Lepeleire I, Van Hecken A, Verbesselt R, et al. Lack of interaction between famotidine and warfarin. Int J Clin Pharmacol Res. 1990;10(3):167-71.
3. Prilosec Prescribing Information WARNINGS.
4. FDA Drug Safety Commission. FDA Drug Safety Communication: Clostridium difficile associated diarrhea can be associated with stomach acid drugs known as proton pump inhibitors (PPIs). Accessed April 8, 2021. https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-clostridium-difficile-associated-diarrhea-can-be-associated-stomach
5. Hatlebakk JG, Katz PO, Camacho-Lobato L, Castell DO. Proton pump inhibitors: better acid suppression when taken before a meal than without a meal. Aliment Pharmacol Ther. 2000;14(10):1267-1272.