The Science Behind IMODIUM®

IMODIUM® contains Loperamide, an anti-motility medicine that works by modulating the gut to help reduce the frequency and urgency of bowel movements to a more normal rhythm.

By acting on receptors in the intestinal wall1 , it modulates the contractions of the muscles in the intestines. This allows more time for water, electrolytes, and nutrients to be absorbed, resulting in firmer stools and relief from diarrhea symptoms.

IMODIUM® is the #1 doctor-recommended brand of OTC anti-diarrheal for over 20 years and starts to work with just one dose to relieve diarrhea, starting to work in one hour to ease symptoms and alleviate patient discomfort.

Did you know?

Loperamide modulates the bowel’s rapid movement allowing the body to reabsorb more water and electrolytes.

Acute diarrhea

During acute diarrhea, intestinal motility is increased. Due to the faster intestinal transit, less water and nutrients can be absorbed from the food.

... treated with loperamide

Loperamide modulates bowel movements. The body has more time to absorb water and important nutrients. At the same time, the increased secretion into the intestine is reduced. Increased fluid loss can be counteracted by the fast action of Loperamide.

_{References: 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163293/}