LISTERINE® and the ADA Seal of Acceptance

Learn how LISTERINE^® Brand rinses have achieved the ADA Seal of Acceptance

LISTERINE® ANTISEPTIC IS THE ONLY NATIONALLY BRANDED OTC ANTISEPTIC MOUTHWASH THAT HAS EARNED THE ADA SEAL OF ACCEPTANCE TO PREVENT AND REDUCE PLAQUE AND GINGIVITIS1*

The ADA Council on Scientific Affairs has adopted specific guidelines to earn the ADA Seal of Acceptance for the Chemotherapeutic Products for Control of Gingivitis category.¹

2 independent 6-month clinical studies, utilizing a placebo control, showing significant reduction in gingivitis for the test product vs the control^2,3
Data showing that plaque bacteria do not become resistant to the test product⁴
Data showing that test product does not allow pathogenic or opportunistic plaque bacteria to flourish⁴
Data showing that oral soft tissues and teeth are not harmed⁴
Toxicology and mutagenicity studies to assess possible adverse effects at the cellular level⁴

The ADA sets high standards—including two 6-month studies showing a minimum 15% reduction in gingivitis and a mean of no less than 20% across the two studies—before awarding the seal.

The LISTERINE® Brand is proud to reach these rigorous and thorough standards set by the ADA. Additionally, the ADA has accepted LISTERINE® TOTAL CARE, LISTERINE® TOTAL CARE ZERO and LISTERINE® SMART RINSE® into its group of fluoride products permitted to bear the ADA seal.

_{*The ADA Council on Scientific Affairs’ Acceptance of LISTERINE® Antiseptic is based on its finding that the product is effective in helping to prevent or reduce gingivitis and plaque above the gumline, when used as directed.}

_{References: 1.}_{American Dental Association. ADA seal product report: Listerine® antiseptic. ADA Web site. Accessed May 9, 2014.}_2._{Lamster IB, Alfano MC, Seiger MC, Gordon JM. The effect of LISTERINE® Antiseptic on reduction of existing plaque and gingivitis.}_{Clin Prev Dent.}_{1983;5:12-16.}_3._{Minah GE, DePaola LG, Overholser CD, et al. Effects of 6 months use of an antiseptic mouthrinse on supragingival dental plaque microflora.}_{J Clin Periodontol.}_{1989;16:347-352.}_4._{Data on file, Johnson & Johnson Consumer Inc.}