In a randomized, controlled, single-centre, examiner-blind, parallel-group study, the anti-plaque and anti-gingivitis efficacy of LISTERINE® ZERO® (alcohol-free mouthrinse) and LISTERINE® COOL MINT® (alcohol-containing mouthrinse) showed no statistically significant differences.
Alcohol-free and alcohol-containing EO mouthrinses were both demonstrated to reduce plaque, gingivitis, and gingival bleeding in comparison to the use of mechanical oral hygiene alone.
Figures: a) Mean modified gingival index (MGI), b) plaque index (PI), and c) gingival bleeding index (BI) at baseline, 1, 3, and 6 months across all treatment groups. Baseline values were based on raw scores, and post-baseline means are based on adjusted means. MOH: mechanical oral hygiene; AFM: alcohol-free essential oil mouthrinse; ACM: alcohol-containing essential oil mouthrinse; SE: standard error; *** p < 0.001
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